A simple measure of voluntary control of breathing is an effective physio‐marker for differentiating MCI from mild AD patients and MCI/AD patients from cognitively normal controls
Vasilis Marmarelis, Helena C Chui, Sandra A Billinger, Elizabeth B Joe, Dae Shin, Suhaib Hashem, Jasmin Rizko, Emily Hazen, Danilo Cardim, Rong Zhang · 2025
Read A simple measure of voluntary control of breathing is an effective physio‐marker for differentiating MCI from mild AD patients and MCI/AD patients from cognitively normal controls by Vasilis Marmarelis, Helena C Chui, Sandra A Billinger, Elizabeth B Joe, Dae Shin, Suhaib Hashem, Jasmin Rizko, Emily Hazen, Danilo Cardim, Rong Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715655.txt.
Description
Vasilis Marmarelis and co-authors tested in 2025 whether a simple breathing measure can separate people with memory decline from healthy controls. Control of breathing is often impaired in mild cognitive impairment and Alzheimer's disease. The team recorded breathing while people followed a slow metronome pace at rest.
They computed how much the breathing rate varied from breath to breath during paced breathing. That variation was higher in patients than in controls, and highest in those with mild Alzheimer's disease. The gaps between all groups were clear and statistically strong. The authors present this cheap, non-invasive measure as a useful marker to help sort patients by stage of decline.
Catalog record
| CREATOR | Vasilis Marmarelis, Helena C Chui, Sandra A Billinger, Elizabeth B Joe, Dae Shin, Suhaib Hashem, Jasmin Rizko, Emily Hazen, Danilo Cardim, Rong Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |