Microstructural assessment of the locus coeruleus‐entorhinal cortex pathway and association with ATN markers in patients with cognitive impairment

Marco Aiello, Pasquale Borrelli, Carlo Cavaliere, Moira Marizzoni, Federica Ribaldi, Valentina Garibotto, Max Scheffler, Ileana O Jelescu, Jorge Jovicich, Marco Salvatore, Giovanni B Frisoni, Michela Pievani · 2025

Read Microstructural assessment of the locus coeruleus‐entorhinal cortex pathway and association with ATN markers in patients with cognitive impairment by Marco Aiello, Pasquale Borrelli, Carlo Cavaliere, Moira Marizzoni, Federica Ribaldi, Valentina Garibotto, Max Scheffler, Ileana O Jelescu, Jorge Jovicich, Marco Salvatore, Giovanni B Frisoni, Michela Pievani (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715629.txt.

Description

Marco Aiello and co-authors report a 2025 brain scan study of patients from a memory clinic in Geneva. The team looked at a small path that links two brain areas tied to memory. They checked how the path relates to signs of amyloid, tau, and loss of brain tissue.

One hundred twenty four people took part, with no impairment, mild impairment, or dementia. Scans of the path differed most for people with tau in one key area and for people with tissue loss. One scan measure also linked to diagnosis and test scores apart from the other markers. The path may add fresh detail beyond the standard signs used in clinic.

Catalog record

CREATORMarco Aiello, Pasquale Borrelli, Carlo Cavaliere, Moira Marizzoni, Federica Ribaldi, Valentina Garibotto, Max Scheffler, Ileana O Jelescu, Jorge Jovicich, Marco Salvatore, Giovanni B Frisoni, Michela Pievani
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715629

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