Associations between imaging biomarkers and sleep quality in the U.S. POINTER study baseline cohort
Joseph R. Winer, Tyler J. Ward, Margaret Scales, Jacinda Taggett, Marjorie Howard, Katie L Stone, Samuel N. Lockhart, Laura D Baker, Kathleen M. Hayden, Susan M. Landau, Theresa M. Harrison, The U.S. POINTER Study Group · 2025
Read Associations between imaging biomarkers and sleep quality in the U.S. POINTER study baseline cohort by Joseph R. Winer, Tyler J. Ward, Margaret Scales, Jacinda Taggett, Marjorie Howard, Katie L Stone, Samuel N. Lockhart, Laura D Baker, Kathleen M. Hayden, Susan M. Landau, Theresa M. Harrison, The U.S. POINTER Study Group (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715498.txt.
Description
A large team reports 2025 baseline results from the U.S. POINTER trial, which follows older adults at higher risk for memory loss. The study links watch-based sleep measures with brain scans in 454 people. Scans cover brain size, white matter damage, and markers tied to Alzheimer disease.
Sleep length showed a U-shaped link with brain health, so both short and long sleep near six to seven hours went with worse scan results. Sleep length did not track memory test scores or the two Alzheimer markers. The links held mainly in people with no sign of amyloid in the brain.
Catalog record
| CREATOR | Joseph R. Winer, Tyler J. Ward, Margaret Scales, Jacinda Taggett, Marjorie Howard, Katie L Stone, Samuel N. Lockhart, Laura D Baker, Kathleen M. Hayden, Susan M. Landau, Theresa M. Harrison, The U.S. POINTER Study Group |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |