Evaluating the Effects of LDL Cholesterol Levels on Tau Visualization in [F‐18]flortaucipir PET Scans
Jaipal Virdi, Daniel H Silverman · 2025
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Description
Jaipal Virdi and Daniel Silverman ask whether blood cholesterol skews a brain scan for Alzheimer disease in a 2025 study. The scan uses a tracer that sticks to tau, a protein that tangles in the disease. The tracer also sticks where it should not, and fatty cholesterol carriers were a suspect.
Data came from a large Alzheimer study network for 56 people, from sharp minds to full disease. The team set each person's LDL cholesterol share against tracer uptake in brain zones. The two tracked together in a clear way. The authors say cholesterol may cloud how the tau signal should be read in clinic and trials.
Catalog record
| CREATOR | Jaipal Virdi, Daniel H Silverman |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |