Mitochondrial DNA copy number from human blood is associated with specific cognitive function
Qu Tian, David A. Zweibaum, Richard Oppong, Yong Qian, Luke C Pilling, Francesco Casanova, Janice L Atkins, David Melzer, Jun Ding, Luigi Ferrucci · 2025
Read Mitochondrial DNA copy number from human blood is associated with specific cognitive function by Qu Tian, David A. Zweibaum, Richard Oppong, Yong Qian, Luke C Pilling, Francesco Casanova, Janice L Atkins, David Melzer, Jun Ding, Luigi Ferrucci (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715343.txt.
Description
Qu Tian and co-authors tied the count of cell power-plant gene copies in blood to one kind of thought skill. Power plants, called mitochondria, hold their own small ring of genes. The count of those rings in blood has been tied to dementia risk in past work. Which thought skills it tracks, and whether frailty bends the link, stayed unclear.
The team read gene data from the UK Biobank, a huge health bank. Thought tests came about nine years after the blood was drawn, in more than thirteen thousand adults. More gene copies went with a higher score on a fast symbol-swap test of speed. The count showed no clear link to the other tests of mind skills. The team also split the group by frailty and by load of gene flaws to test if those states shift the link.
Catalog record
| CREATOR | Qu Tian, David A. Zweibaum, Richard Oppong, Yong Qian, Luke C Pilling, Francesco Casanova, Janice L Atkins, David Melzer, Jun Ding, Luigi Ferrucci |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |