Cognition‐related Network Organization in Parkinson's Disease with Mild Cognitive Impairment and Dementia

Yoshikazu Nakano, An Vo, Nha Nguyen, Chris C Tang, David Eidelberg · 2025

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Description

Yoshikazu Nakano, An Vo, Nha Nguyen, Chris Tang, and David Eidelberg study how brain networks change as Parkinson's disease affects thinking. They use a known activity pattern for cognition in Parkinson's, drawn from brain scans, and measure how its regions link to each other. Their 2025 study covers 102 patients sorted into four groups, from normal thinking to dementia.

All patients took thinking tests and had metabolism scans of the brain. A measure called assortativity, which tracks whether busy regions link to other busy regions, was much the same in normal and mildly affected patients. It rose in patients with wider mild problems and rose further in dementia. The authors say the measure may warn which patients are moving toward dementia and deserve closer watch.

Catalog record

CREATORYoshikazu Nakano, An Vo, Nha Nguyen, Chris C Tang, David Eidelberg
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715335

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