Brain effects of 5:2 intermittent fasting and the healthy living diet in a randomized controlled trial

Apostolos Manolopoulos, Roger J Mullins, Francheska Delgado‐Peraza, Maja Mustapic, Carlos Nogueras‐Ortiz, Pamela J Yao, Mark R Cookson, Josephine M Egan, Sophia Frangou, Mark P Mattson, Dimitrios Kapogiannis · 2025

Read Brain effects of 5:2 intermittent fasting and the healthy living diet in a randomized controlled trial by Apostolos Manolopoulos, Roger J Mullins, Francheska Delgado‐Peraza, Maja Mustapic, Carlos Nogueras‐Ortiz, Pamela J Yao, Mark R Cookson, Josephine M Egan, Sophia Frangou, Mark P Mattson, Dimitrios Kapogiannis (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715314.txt.

Description

Apostolos Manolopoulos and co-authors ran a trial that set a part-time fast diet against a plain healthy diet. Both ran for eight weeks in adults whose bodies use sugar poorly, a state tied to brain aging. The fast plan cut food hard on two days a week and left the rest free. The other plan just spread sound food rules across all days.

Forty adults past age fifty-five with sharp thought took part. Both diets eased brain signs of poor sugar use and trimmed a scan-based brain-age gap. Both also raised scores on tests of planning and memory, and cut weight and waist size. Signs of the disease itself in blood and spinal fluid did not move. The fast plan leaned a bit ahead on some counts, but not by a clear edge.

Catalog record

CREATORApostolos Manolopoulos, Roger J Mullins, Francheska Delgado‐Peraza, Maja Mustapic, Carlos Nogueras‐Ortiz, Pamela J Yao, Mark R Cookson, Josephine M Egan, Sophia Frangou, Mark P Mattson, Dimitrios Kapogiannis
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715314

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