Decreased levels of CSF CXCL8 in clinical and biological profiles of Alzheimer's disease: results of a cohort of Brazilian older adults
Ivonne Carolina Bolaños Burgos, Júlia de Almeida Barreto, Caio Mendes Ribeiro, Pedro Henrique Oliveira Aquino, Ana Paula Bernardes Real, Aline Siqueira de Souza, Aloisio Joaquim Freitas Ribeiro, Lourdes Coral Contreras Montenegro, Gabriela Tomé Oliveira Engelmann, Erika de Oliveira Hansen, Natália S · 2025
Read Decreased levels of CSF CXCL8 in clinical and biological profiles of Alzheimer's disease: results of a cohort of Brazilian older adults by Ivonne Carolina Bolaños Burgos, Júlia de Almeida Barreto, Caio Mendes Ribeiro, Pedro Henrique Oliveira Aquino, Ana Paula Bernardes Real, Aline Siqueira de Souza, Aloisio Joaquim Freitas Ribeiro, Lourdes Coral Contreras Montenegro, Gabriela Tomé Oliveira Engelmann, Erika de Oliveira Hansen, Natália S (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715265.txt.
Description
Ivonne Bolaños Burgos and a large team wrote a 2025 study on a swelling signal in the spinal fluid of older Brazilians. The signal, CXCL8, draws immune cells to sites of harm. In Alzheimer's disease, it may react with the disease's key proteins and add to harm. The team measured it across patient groups.
They sorted a group of older adults by thinking profile: disease, mild loss, or normal. Spinal fluid gave levels of the signal plus known disease markers. They also sorted the group by a lab-based scheme for disease stage. Levels of the signal ran lower in disease profiles, a result the title reports.
Catalog record
| CREATOR | Ivonne Carolina Bolaños Burgos, Júlia de Almeida Barreto, Caio Mendes Ribeiro, Pedro Henrique Oliveira Aquino, Ana Paula Bernardes Real, Aline Siqueira de Souza, Aloisio Joaquim Freitas Ribeiro, Lourdes Coral Contreras Montenegro, Gabriela Tomé Oliveira Engelmann, Erika de Oliveira Hansen, Natália S |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |