The impact of tau‐PET in a selected memory clinic cohort: design and rationale of the TAP‐TAU study
Marie R. Vermeiren, Joost Somsen, Gert Luurtsema, Fransje E. Reesink, Nicolaas A. Verwey, Liesbeth Hempenius, Nelleke Tolboom, Geert Jan Biessels, J. Matthijs Biesbroek, Meike W. Vernooij, Sophie E.M. Veldhuijzen van Zanten, Harro Seelaar, Emma M. Coomans, Charlotte Teunissen, Afina Willemina Lemstr · 2025
Read The impact of tau‐PET in a selected memory clinic cohort: design and rationale of the TAP‐TAU study by Marie R. Vermeiren, Joost Somsen, Gert Luurtsema, Fransje E. Reesink, Nicolaas A. Verwey, Liesbeth Hempenius, Nelleke Tolboom, Geert Jan Biessels, J. Matthijs Biesbroek, Meike W. Vernooij, Sophie E.M. Veldhuijzen van Zanten, Harro Seelaar, Emma M. Coomans, Charlotte Teunissen, Afina Willemina Lemstr (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715203.txt.
Description
Marie Vermeiren and co-authors lay out the design of a study on a brain scan for Alzheimer's disease, in a 2025 paper. The scan, tau-PET, pictures the tau tangles that mark the disease and separates it well from other dementias in research settings. Whether it changes real clinic decisions was untested.
Their study, TAP-TAU, will enroll three hundred patients at six Dutch memory clinics whose diagnosis stays uncertain after routine checks, with Alzheimer's among the possibilities. Each patient receives the scan, blood marker tests, and wellbeing surveys. The team will compare diagnosis, confidence, care plans, and patient wellbeing before and after the scan. They will also weigh the scan against cheaper blood tools. The paper explains why this hand-picked, uncertain group is where the scan must prove itself.
Catalog record
| CREATOR | Marie R. Vermeiren, Joost Somsen, Gert Luurtsema, Fransje E. Reesink, Nicolaas A. Verwey, Liesbeth Hempenius, Nelleke Tolboom, Geert Jan Biessels, J. Matthijs Biesbroek, Meike W. Vernooij, Sophie E.M. Veldhuijzen van Zanten, Harro Seelaar, Emma M. Coomans, Charlotte Teunissen, Afina Willemina Lemstr |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |