Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer's continuum: a prospective cohort study
Jiwei Jiang, Wenyi Li, Shirui Jiang, Jun Xu · 2025
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Description
The size of a fluid-making fold in the brain may mark Alzheimer's disease, Jiwei Jiang and co-authors report in a 2025 study. The fold, called the choroid plexus, makes spinal fluid and guards the brain. Six hundred seven adults in a Chinese cohort took part: healthy adults, adults with mild memory loss, and adults with Alzheimer's dementia.
Brain scans measured fold size, while fluid tests tracked hallmark disease proteins. Memory, mood, and daily life scores were also collected. Tests weigh whether fold size links fluid marks to thinking scores, and whether it can flag plaque buildup. A cheap scan marker of this kind could aid early diagnosis where costly fluid tests are scarce.
Catalog record
| CREATOR | Jiwei Jiang, Wenyi Li, Shirui Jiang, Jun Xu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |