Assessing the impact of fasting condition and storage time on plasma Amyloid‐β 42 and 40, pTau181, Nf‐L and GFAP measurements

Helena Blasco‐Forniés, Javier Torres‐Torronteras, Paula Ortiz‐Romero, Armand González Escalante, Carolina Minguillón, Federica Anastasi, Esther Jiménez‐Moyano, Marc Suárez‐Calvet, Marta del Campo · 2025

Read Assessing the impact of fasting condition and storage time on plasma Amyloid‐β 42 and 40, pTau181, Nf‐L and GFAP measurements by Helena Blasco‐Forniés, Javier Torres‐Torronteras, Paula Ortiz‐Romero, Armand González Escalante, Carolina Minguillón, Federica Anastasi, Esther Jiménez‐Moyano, Marc Suárez‐Calvet, Marta del Campo (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715159.txt.

Description

Helena Blasco-Forniés and eight co-authors wrote this 2025 conference study on two practical worries for Alzheimer's blood tests. Blood markers can flag the disease, but clinics need to know whether a recent meal or years in a freezer skew the readings. The team tested both questions in a Spanish research cohort.

Samples taken while fasting held less of two amyloid markers than fed samples, yet their ratio, the value doctors lean on, stayed steady. Three other markers showed no meal effect at all. After ten years in deep freeze, amyloid readings ran higher and two other markers ran lower, while the key tau marker held firm. The markers still spotted disease just as well in both meal states. The authors advise noting storage time when labs compare old samples.

Catalog record

CREATORHelena Blasco‐Forniés, Javier Torres‐Torronteras, Paula Ortiz‐Romero, Armand González Escalante, Carolina Minguillón, Federica Anastasi, Esther Jiménez‐Moyano, Marc Suárez‐Calvet, Marta del Campo
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715159

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