Proteomic Analysis Resolves Distinct Molecular Signatures in Alzheimer’s Disease Brain Across Diverse Racial Groups
Fatemeh Seifar, Edward J Fox, Anantharaman Shantaraman, Yue Liu, Erica S Modeste, Duc M Duong, Luming Yin, Marla Gearing, James J Lah, Joseph S Reddy, Mariet Allen, Zachary Quicksall, Laura M Heath, Jo Scanlan, Erming Wang, Minghui Wang, Abby Vander Linden, William L Poehlman, Xianfeng Chen, Saurabh · 2025
Read Proteomic Analysis Resolves Distinct Molecular Signatures in Alzheimer’s Disease Brain Across Diverse Racial Groups by Fatemeh Seifar, Edward J Fox, Anantharaman Shantaraman, Yue Liu, Erica S Modeste, Duc M Duong, Luming Yin, Marla Gearing, James J Lah, Joseph S Reddy, Mariet Allen, Zachary Quicksall, Laura M Heath, Jo Scanlan, Erming Wang, Minghui Wang, Abby Vander Linden, William L Poehlman, Xianfeng Chen, Saurabh (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715113.txt.
Description
Fatemeh Seifar and co-authors map protein signatures in Alzheimer disease brains across racial groups. Their twenty twenty-five study answers a skew in the field: most Alzheimer knowledge rests on non-Hispanic White samples. A national partnership built diverse brain data to close that gap.
Protein reads from post-mortem brain tissue were compared across groups. Distinct molecular patterns emerged that past single-group work had blurred. The huge team joins brain banks and analysis centers across the United States. Such maps matter because a drug or test built on one group biology may miss others. The work sets a broader base for diagnosis and treatment design.
Catalog record
| CREATOR | Fatemeh Seifar, Edward J Fox, Anantharaman Shantaraman, Yue Liu, Erica S Modeste, Duc M Duong, Luming Yin, Marla Gearing, James J Lah, Joseph S Reddy, Mariet Allen, Zachary Quicksall, Laura M Heath, Jo Scanlan, Erming Wang, Minghui Wang, Abby Vander Linden, William L Poehlman, Xianfeng Chen, Saurabh |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |