Early and Genetic Biomarkers in Alzheimer's Disease: Role of Metabolism and Neuroinflammation in the Cognition of Coastal Peruvians
Jonathan Adrian Zegarra‐Valdivia, Harold Alessandro Arana‐Nombera, Leandro Aron Perez‐Fernandez, Milagros del Rocio Casimiro‐Arana, Reyna Elizabeth Alamo‐Medina, Viviana Nayelli Gallegos‐Manayay, María del Rosario Oliva‐Piscoya, Eduardo Sebastián Abanto‐Saldaña, Nobuko Vásquez‐Zuñe, Maria Celinda Cr · 2025
Read Early and Genetic Biomarkers in Alzheimer's Disease: Role of Metabolism and Neuroinflammation in the Cognition of Coastal Peruvians by Jonathan Adrian Zegarra‐Valdivia, Harold Alessandro Arana‐Nombera, Leandro Aron Perez‐Fernandez, Milagros del Rocio Casimiro‐Arana, Reyna Elizabeth Alamo‐Medina, Viviana Nayelli Gallegos‐Manayay, María del Rosario Oliva‐Piscoya, Eduardo Sebastián Abanto‐Saldaña, Nobuko Vásquez‐Zuñe, Maria Celinda Cr (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715104.txt.
Description
Jonathan Zegarra-Valdivia and co-authors set out a study protocol on early markers of Alzheimer disease in coastal Peru. Low resource countries lack useful early biomarkers, and genetic risk factors in Peruvians are unknown. The project builds the first serum bank in the north of the country for this work.
Adults over age 50 with healthy cognition, mild impairment, or Alzheimer disease will be compared in a case control design. The team will profile thinking skills and measure blood markers tied to metabolism and inflammation, including a growth factor and several signaling proteins. Genetic risk and protection factors will also be assessed. Early results are still in progress as the cohort is assembled.
Catalog record
| CREATOR | Jonathan Adrian Zegarra‐Valdivia, Harold Alessandro Arana‐Nombera, Leandro Aron Perez‐Fernandez, Milagros del Rocio Casimiro‐Arana, Reyna Elizabeth Alamo‐Medina, Viviana Nayelli Gallegos‐Manayay, María del Rosario Oliva‐Piscoya, Eduardo Sebastián Abanto‐Saldaña, Nobuko Vásquez‐Zuñe, Maria Celinda Cr |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |