Distinct Association of Amyloid and Vascular Pathologies with Enhanced Perivascular Spaces

Woo Sik Kim, Roh‐Eul Yoo, Yejin Hwang, Yelim Yang, Joon‐Kyung Seong, Seung Hong Choi, Wha Jin Lee · 2025

Read Distinct Association of Amyloid and Vascular Pathologies with Enhanced Perivascular Spaces by Woo Sik Kim, Roh‐Eul Yoo, Yejin Hwang, Yelim Yang, Joon‐Kyung Seong, Seung Hong Choi, Wha Jin Lee (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715090.txt.

Description

Woo Sik Kim and six co-authors mapped tiny fluid-filled gaps around brain vessels in a mixed dementia group. Wider gaps are read as a sign that the brain's wash-out system works poorly. Such gaps show in both Alzheimer's disease and vessel-based dementia. The team asked if the place of the gaps tells the two apart.

The Seoul cohort held ninety-nine adults with sharp thought and one hundred ninety with weak thought. Experts sorted the weak group by amyloid load and vessel harm from scans. A smart tool then gauged gap size by brain zone. In the amyloid groups, gaps grew most at the side and back of the brain. In the vessel-harm groups, gaps grew in all zones, most of all in a deep core zone. Place, not just size, may thus mark which ill is at work.

Catalog record

CREATORWoo Sik Kim, Roh‐Eul Yoo, Yejin Hwang, Yelim Yang, Joon‐Kyung Seong, Seung Hong Choi, Wha Jin Lee
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715090

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