Resting State Functional Connectivity Assessment of Healthy Aging Trajectories in the Marmoset Brain

Rebecca Bhik‐Ghanie, Diego Szczupak, Bei Zhang, Daniel Papoti, Vinicius Campos, Lauren R Dubberley, T Kevin Hitchens, Fang‐Cheng Yeh, Lauren K Hayrynen Schaeffer, Gregory W Carter, Stacey J Sukoff Rizzo, David J Schaeffer, Afonso C Silva · 2025

Read Resting State Functional Connectivity Assessment of Healthy Aging Trajectories in the Marmoset Brain by Rebecca Bhik‐Ghanie, Diego Szczupak, Bei Zhang, Daniel Papoti, Vinicius Campos, Lauren R Dubberley, T Kevin Hitchens, Fang‐Cheng Yeh, Lauren K Hayrynen Schaeffer, Gregory W Carter, Stacey J Sukoff Rizzo, David J Schaeffer, Afonso C Silva (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715056.txt.

Description

Rebecca Bhik-Ghanie and co-authors chart healthy brain aging in marmosets in a 2025 study. The common marmoset is a prized model for brain disease, with a primate-style expanded frontal cortex, and a new consortium is building gene-edited marmosets at risk for Alzheimer's disease.

To set the baseline, the team scanned 25 marmosets, from youngsters of eight months to elders of one hundred fifty months, on a high-field MRI machine. The animals, trained to rest calmly in holders, gave resting-state scans that reveal how brain networks link up at rest. Mapping how those links shift across a normal lifespan gives the consortium a yardstick. Future scans of at-risk animals can then be read against healthy change, not guesswork.

Catalog record

CREATORRebecca Bhik‐Ghanie, Diego Szczupak, Bei Zhang, Daniel Papoti, Vinicius Campos, Lauren R Dubberley, T Kevin Hitchens, Fang‐Cheng Yeh, Lauren K Hayrynen Schaeffer, Gregory W Carter, Stacey J Sukoff Rizzo, David J Schaeffer, Afonso C Silva
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715056

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