Myelin water imaging with clinically feasible scan time: The accelerated BMC‐mcDESPOT (aBMC‐mcDESPOT) method

Jonghyun Bae, Zhaoyuan Gong, Alex Guo, John P Laporte, Mary E Faulkner, Mustapha Bouhrara · 2025

Read Myelin water imaging with clinically feasible scan time: The accelerated BMC‐mcDESPOT (aBMC‐mcDESPOT) method by Jonghyun Bae, Zhaoyuan Gong, Alex Guo, John P Laporte, Mary E Faulkner, Mustapha Bouhrara (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11715038.txt.

Description

Jonghyun Bae and five co-authors speed up a brain scan method that maps the fatty wraps on nerve fibers. Those wraps, called myelin, thin with age and disease, so maps of their water share guide care and trials. The base method needed about seventeen minutes of scan time, too long for busy clinics. Their 2025 work cuts that to about six.

Two tricks combine: fewer scan passes, and keeping just the best shots from one pass type. Maps from the fast scans matched the slow ones in pattern, with modest error. Repeat scans held steady as well. A slight bias showed, but white matter bounds stayed tight. The authors call the fast method fit for clinic use and trials.

Catalog record

CREATORJonghyun Bae, Zhaoyuan Gong, Alex Guo, John P Laporte, Mary E Faulkner, Mustapha Bouhrara
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11715038

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