Urine dicarboxylic acid as a potential AD biomarker associated with fusiform gyrus volume in older cognitively healthy adults
Alfred N Fonteh, Salvador Maldonado, Ryan Butler, Jimmy Kang, Thomas Macias, Anne Nolty, J Yu, Wendy J Mack, Helena C Chui, Yafa Minazad, Robert A Kloner, Xianghong Arakaki · 2025
Read Urine dicarboxylic acid as a potential AD biomarker associated with fusiform gyrus volume in older cognitively healthy adults by Alfred N Fonteh, Salvador Maldonado, Ryan Butler, Jimmy Kang, Thomas Macias, Anne Nolty, J Yu, Wendy J Mack, Helena C Chui, Yafa Minazad, Robert A Kloner, Xianghong Arakaki (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714926.txt.
Description
A simple urine test for Alzheimer's risk would be cheap and painless. Alfred Fonteh and co-authors tested whether certain acids in urine track brain size in healthy older adults. They enrolled sixty-two adults over sixty-five with normal thinking. Each gave urine samples and had a brain scan. Lab work measured a family of acids, and the team compared acid shares with the sizes of brain regions.
One acid group showed a clear link with the fusiform gyrus, a region used in face and word reading. Higher shares of that group went with a smaller region. A ratio of two acid groups showed the reverse link. The authors present the acids as a possible early marker worth testing in larger groups.
Catalog record
| CREATOR | Alfred N Fonteh, Salvador Maldonado, Ryan Butler, Jimmy Kang, Thomas Macias, Anne Nolty, J Yu, Wendy J Mack, Helena C Chui, Yafa Minazad, Robert A Kloner, Xianghong Arakaki |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |