Vulnerability of locus coeruleus projections during aging
Blanca Zufiria‐Gerboles, Daniel Veréb, Joana B Pereira · 2025
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Description
Blanca Zufiria-Gerboles, Daniel Vereb, and Joana B. Pereira report a 2025 scan study of a small but key brain hub with age. The hub sends a chemical signal across much of the brain and helps with alertness and memory. The team used brain scans from six hundred and eighteen adults aged eighteen to eighty-eight. They traced the paths that link this hub to the rest of the brain.
Those links grew weaker with age in many areas, including parts linked to memory and choice. People who said they had memory problems showed a stronger link to one mood-related area. People with high blood pressure or diabetes had weaker links to some of the same core areas. Low mood and poor sleep were also tied to weaker links. The results suggest the hub's paths fade both with age and with common health problems.
Catalog record
| CREATOR | Blanca Zufiria‐Gerboles, Daniel Veréb, Joana B Pereira |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |