DeepSUVR: Using temporal constraints to improve SUVR and Centiloid quantification

Pierrick Bourgeat, Jurgen Fripp, Ashley G Gillman, Timothy Cox, Manu S Goyal, Duygu Tosun, Pamela LaMontagne, Tammie LS Benzinger, Michael S W Weiner, Victor L Villemagne, Colin L Masters, Christopher C Rowe, Vincent Dore, for the Alzheimer’s Disease Neuroimaging Initiative, OASIS3, and the AIBL res · 2025

Read DeepSUVR: Using temporal constraints to improve SUVR and Centiloid quantification by Pierrick Bourgeat, Jurgen Fripp, Ashley G Gillman, Timothy Cox, Manu S Goyal, Duygu Tosun, Pamela LaMontagne, Tammie LS Benzinger, Michael S W Weiner, Victor L Villemagne, Colin L Masters, Christopher C Rowe, Vincent Dore, for the Alzheimer’s Disease Neuroimaging Initiative, OASIS3, and the AIBL res (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714815.txt.

Description

A brain scan that counts amyloid, the Alzheimer's plaque stuff, leans on a quiet patch of brain as its zero. Bourgeat and co-authors fix that zero's wobble in 2025 with a learned corrector. Noise, spill, and stray binding in the patch all bend the count.

The network trains on repeat visits: true plaque shifts slowly, so wild swings get punished. It learns a fix factor for each scan. The shelf is large: 3,098 people, 8,826 scans, from three great study pools. The count it cleans feeds the field's shared centiloid scale. Surer counts mean surer trial reads, and surer calls on who holds the disease.

Catalog record

CREATORPierrick Bourgeat, Jurgen Fripp, Ashley G Gillman, Timothy Cox, Manu S Goyal, Duygu Tosun, Pamela LaMontagne, Tammie LS Benzinger, Michael S W Weiner, Victor L Villemagne, Colin L Masters, Christopher C Rowe, Vincent Dore, for the Alzheimer’s Disease Neuroimaging Initiative, OASIS3, and the AIBL res
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714815

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