Renal Atrophy Relates to Brain Volume Loss on 7,149 MRI Scans

Somayeh Meysami, Cyrus A. Raji, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A. Merrill, Rajpaul Attariwala · 2025

Read Renal Atrophy Relates to Brain Volume Loss on 7,149 MRI Scans by Somayeh Meysami, Cyrus A. Raji, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A. Merrill, Rajpaul Attariwala (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714685.txt.

Description

Somayeh Meysami and co-authors link shrinking kidneys to loss of brain volume in a 2025 study. Kidney shrinkage may mark long-term vessel damage in the body. If so, kidney size could offer a window on brain aging and Alzheimer risk. The team tested that idea with whole-body scans.

Scans came from 7,149 healthy adults at four sites, with a mean age of about 53. A deep learning tool split the brain into 96 regions and measured each one. Kidney volumes were measured from the same scans. Links between kidney and brain size were checked while accounting for sex and head size. The large sample gives the kidney-brain link a firm test in healthy people.

Catalog record

CREATORSomayeh Meysami, Cyrus A. Raji, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A. Merrill, Rajpaul Attariwala
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714685

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