Additive Impact of Cardiometabolic Multimorbidity and Depression on Cognitive Decline: Findings from Multi‐Regional Cohorts and Generalization from Community to Clinic
Xuhao Zhao, Yifan Yan, Darren M Lipnicki, Ting Pang, Christopher Chen, Tien Yin Wong, Ching Yu Cheng, Narayanaswamy Venketasubramanian, Eddie Chong, Erico Costa, Richard B Lipton, Mindy J Katz, Karen Ritchie, Isabelle Carriere, Nikolaos Scarmeas, Oye Gureje, Hugh C Hendrie, Sujuan Gao, Ricardo Olive · 2025
Read Additive Impact of Cardiometabolic Multimorbidity and Depression on Cognitive Decline: Findings from Multi‐Regional Cohorts and Generalization from Community to Clinic by Xuhao Zhao, Yifan Yan, Darren M Lipnicki, Ting Pang, Christopher Chen, Tien Yin Wong, Ching Yu Cheng, Narayanaswamy Venketasubramanian, Eddie Chong, Erico Costa, Richard B Lipton, Mindy J Katz, Karen Ritchie, Isabelle Carriere, Nikolaos Scarmeas, Oye Gureje, Hugh C Hendrie, Sujuan Gao, Ricardo Olive (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714637.txt.
Description
Xuhao Zhao and co-authors pool cohorts from around the world in a 2025 study of how heart and metabolic illness plus low mood jointly wear down thinking. Each factor alone is tied to decline, but their combined weight was less clear.
Data from fourteen long term cohorts across six regions were aligned into one record set. People with two or more heart or metabolic ills and signs of low mood showed the steepest slide in thought scores over time. Three clinic based checks tested whether the pattern holds beyond town samples. The work frames joint care of body and mood as a guard for the aging mind.
Catalog record
| CREATOR | Xuhao Zhao, Yifan Yan, Darren M Lipnicki, Ting Pang, Christopher Chen, Tien Yin Wong, Ching Yu Cheng, Narayanaswamy Venketasubramanian, Eddie Chong, Erico Costa, Richard B Lipton, Mindy J Katz, Karen Ritchie, Isabelle Carriere, Nikolaos Scarmeas, Oye Gureje, Hugh C Hendrie, Sujuan Gao, Ricardo Olive |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |