The EEG spectral power ratio as a cognitively relevant marker of preclinical AD

Peter J Fried, Christie Morse, Andrew Northrop, Rushali Patel, Eliza L McKinney, Keya Shah, Danylo Ferreira Cabral, Stephanie S Buss, Christopher Benwell, Recep Ozdemir, Mouhsin Shafi · 2025

Read The EEG spectral power ratio as a cognitively relevant marker of preclinical AD by Peter J Fried, Christie Morse, Andrew Northrop, Rushali Patel, Eliza L McKinney, Keya Shah, Danylo Ferreira Cabral, Stephanie S Buss, Christopher Benwell, Recep Ozdemir, Mouhsin Shafi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714622.txt.

Description

Peter Fried and co-authors test a brain wave ratio as an early flag for Alzheimer's disease. Their 2025 study deals with cerebral slowing, a drift of EEG power from fast to slow bands as the disease brews. A ratio of fast over slow band power captures the drift. Past work found the ratio low in dementia and in amyloid-backed mild decline, and tied it to weaker executive scores.

Here the test turns to symptom-free elders, with a blood amyloid ratio as the stand-in for brain amyloid. Resting EEG, thinking tests, and blood draws came from dozens of older adults. The hunt: does the ratio flag silent disease?

Catalog record

CREATORPeter J Fried, Christie Morse, Andrew Northrop, Rushali Patel, Eliza L McKinney, Keya Shah, Danylo Ferreira Cabral, Stephanie S Buss, Christopher Benwell, Recep Ozdemir, Mouhsin Shafi
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714622

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