TMS‐EEG excitability measures are related to global and local cognitive function in early symptomatic AD
Stephanie S Buss, Recep Ozdemir, Brice Passera, Peter J Fried, Daniel Manning, Isabelle Woods, Grace Desmond, Lynn Shaughnessy, Daniel Z Press, Mouhsin Shafi · 2025
Read TMS‐EEG excitability measures are related to global and local cognitive function in early symptomatic AD by Stephanie S Buss, Recep Ozdemir, Brice Passera, Peter J Fried, Daniel Manning, Isabelle Woods, Grace Desmond, Lynn Shaughnessy, Daniel Z Press, Mouhsin Shafi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714610.txt.
Description
Stephanie Buss and co-authors measure cortical excitability with magnetic stimulation and brain wave reads in early Alzheimer disease, and tie the numbers to thinking scores. The Alzheimer cortex is known to run hot, but most proof comes from the motor area. Whether the parietal lobe, a seat of cognition, also runs hot was open.
Their 2025 study pulses two sites, motor and parietal, in biomarker-confirmed patients and matched controls. Early response strength near each site is the readout. The team sets those reads against global cognition and a parietal-weighted score built for this question. Linking a brain-physiology dial to specific thinking skills could give trials a fast marker of disease state and drug effect.
Catalog record
| CREATOR | Stephanie S Buss, Recep Ozdemir, Brice Passera, Peter J Fried, Daniel Manning, Isabelle Woods, Grace Desmond, Lynn Shaughnessy, Daniel Z Press, Mouhsin Shafi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |