Feasibility of using plasma p‐tau217 as a surrogate for brain Aβ PET in the community
Wasiu Gbolahan Balogun, Rebecca A Deek, Xuemei Zeng, Anuradha Sehrawat, Yijun Chen, Pamela CL Ferreira, Bruna Bellaver, Tara K Lafferty, Guilherme Povala, M Ilyas Kamboh, Victor L Villemagne, William E Klunk, Tharick A Pascoal, Mary Ganguli, Oscar L Lopez, Ann D Cohen, Beth E Snitz, Thomas K Karikar · 2025
Read Feasibility of using plasma p‐tau217 as a surrogate for brain Aβ PET in the community by Wasiu Gbolahan Balogun, Rebecca A Deek, Xuemei Zeng, Anuradha Sehrawat, Yijun Chen, Pamela CL Ferreira, Bruna Bellaver, Tara K Lafferty, Guilherme Povala, M Ilyas Kamboh, Victor L Villemagne, William E Klunk, Tharick A Pascoal, Mary Ganguli, Oscar L Lopez, Ann D Cohen, Beth E Snitz, Thomas K Karikar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714600.txt.
Description
Wasiu Gbolahan Balogun and co-authors test a blood marker as a stand-in for brain scans in work from 2025. The marker, plasma p-tau217, is the best blood sign of amyloid build-up in the brain, but most past studies used selected groups.
Two community cohorts in Pennsylvania took both the blood test and a brain scan. The blood test ruled out amyloid well, with high accuracy for negative results across several assays. But a positive result was often wrong in these general groups. The authors conclude the test can screen but cannot yet replace scans.
Catalog record
| CREATOR | Wasiu Gbolahan Balogun, Rebecca A Deek, Xuemei Zeng, Anuradha Sehrawat, Yijun Chen, Pamela CL Ferreira, Bruna Bellaver, Tara K Lafferty, Guilherme Povala, M Ilyas Kamboh, Victor L Villemagne, William E Klunk, Tharick A Pascoal, Mary Ganguli, Oscar L Lopez, Ann D Cohen, Beth E Snitz, Thomas K Karikar |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |