Mechanistic links of amyloid, atrophy, and cognition profiles for gait disturbance in Alzheimer's disease
Min Seok Baek, Joon‐Kyung Seong, Sung‐Woo Kim, Dong Ho Kim, Jin Yong Hong · 2025
Read Mechanistic links of amyloid, atrophy, and cognition profiles for gait disturbance in Alzheimer's disease by Min Seok Baek, Joon‐Kyung Seong, Sung‐Woo Kim, Dong Ho Kim, Jin Yong Hong (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714592.txt.
Description
Min Seok Baek and co-authors present a 2025 study of walking problems in Alzheimer's disease. They compare patients at early and full stages with healthy peers. Each person had brain scans, thinking tests, gene checks, and a measured walk on a sensor mat.
Walking got slower and steps got shorter as the disease advanced. Time with both feet down rose, and step patterns grew less steady. These changes tied to amyloid build-up in wide brain areas and to thinning in key regions. Their path model runs from amyloid to thinning and poor thinking, and from there to poor walking. The work gives a clear chain that care teams can test and target.
Catalog record
| CREATOR | Min Seok Baek, Joon‐Kyung Seong, Sung‐Woo Kim, Dong Ho Kim, Jin Yong Hong |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |