Ten Year Patterns of Change in HbA1C and Risk of Dementia in a Diverse Cohort of Adults with Type 2 Diabetes

Rachel A. Whitmer, Chris Moran, Brianna Costales, Ai‐Lin Tsai, Mary E Lacy, Andrew Karter, Paola Gilsanz · 2025

Read Ten Year Patterns of Change in HbA1C and Risk of Dementia in a Diverse Cohort of Adults with Type 2 Diabetes by Rachel A. Whitmer, Chris Moran, Brianna Costales, Ai‐Lin Tsai, Mary E Lacy, Andrew Karter, Paola Gilsanz (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714574.txt.

Description

Rachel Whitmer and co-authors examine a 2025 study of blood sugar control over ten years and later dementia risk. All of the adults had type 2 diabetes and lived in Northern California. Their records held repeated measures of a long-term sugar mark. The team sorted more than thirty thousand people into five paths. Some kept low levels for a decade, while others stayed high or rose and fell.

People whose levels stayed in the middle range and peaked at some point had higher dementia risk later. Those with levels that stayed very high had the highest risk of all. People who held levels close to the target range had no extra risk. The pattern held for men and women and across ethnic groups. The work shows that a single sugar test misses the story that a long record can tell.

Catalog record

CREATORRachel A. Whitmer, Chris Moran, Brianna Costales, Ai‐Lin Tsai, Mary E Lacy, Andrew Karter, Paola Gilsanz
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714574

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