Mapping local and distal effects of different neuropathologies on amygdala volume
Amanda Annettesdotter, Katja Selezneva, Amanda E Denning, Anika Wuestefeld, Sadhana Ravikumar, Ranjit Ittyerah, Lisa M Levorse, Madigan Bedard, Eunice Chung, John L Robinson, Theresa Schuck, Eddie B Lee, Sydney A Lim, Winifred Trotman, Alejandra Bahena, David J Irwin, Maria del Mar Arroyo Jimenez, A · 2025
Read Mapping local and distal effects of different neuropathologies on amygdala volume by Amanda Annettesdotter, Katja Selezneva, Amanda E Denning, Anika Wuestefeld, Sadhana Ravikumar, Ranjit Ittyerah, Lisa M Levorse, Madigan Bedard, Eunice Chung, John L Robinson, Theresa Schuck, Eddie B Lee, Sydney A Lim, Winifred Trotman, Alejandra Bahena, David J Irwin, Maria del Mar Arroyo Jimenez, A (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714504.txt.
Description
Amanda Annettesdotter and co-authors map which disease proteins shrink the amygdala, a small brain hub for emotion and memory, in a 2025 conference paper. Many proteins can build up in this hub. It was not clear which ones drive its shrinkage, or whether the harm is local or comes from far areas.
The team studied donated brains from 73 people, with and without brain disease. Fine scans measured the whole hub and, in some cases, its small parts. Raters scored four proteins, tau, amyloid, alpha-synuclein, and TDP-43, in the hub and in nearby memory zones. The team then matched protein scores to hub size. Their aim was to split local effects from effects that arrive from other regions.
Catalog record
| CREATOR | Amanda Annettesdotter, Katja Selezneva, Amanda E Denning, Anika Wuestefeld, Sadhana Ravikumar, Ranjit Ittyerah, Lisa M Levorse, Madigan Bedard, Eunice Chung, John L Robinson, Theresa Schuck, Eddie B Lee, Sydney A Lim, Winifred Trotman, Alejandra Bahena, David J Irwin, Maria del Mar Arroyo Jimenez, A |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |