Comparison of plasma ALZpath p‐Tau217 with Lilly p‐Tau217 and p‐Tau181
Divya Bali, Shorena Janelidze, Gemma Salvadó, Geidy E Serrano, Thomas G Beach, Andreas Jeromin, Oskar Hansson · 2025
Read Comparison of plasma ALZpath p‐Tau217 with Lilly p‐Tau217 and p‐Tau181 by Divya Bali, Shorena Janelidze, Gemma Salvadó, Geidy E Serrano, Thomas G Beach, Andreas Jeromin, Oskar Hansson (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714493.txt.
Description
Divya Bali and co-authors present a conference abstract comparing blood tests for Alzheimer's disease markers in seventy-two older adults whose brains were examined after death. Three assays measuring a phosphorylated tau protein in blood, drawn during life, were set against the plaques and tangles counted at autopsy. Two came from one maker, including a newer tau variant and an older one; the third was the new test under judgement.
All three blood measures rose with plaque load. The established maker's newer assay, though, correlated most strongly with both plaques and tangles, and predicted disease changes more accurately. The test under judgement performed about as well as the older tau assay, and clearly below its same-maker rival. The authors call for replication in larger, independent groups before firm rankings.
Catalog record
| CREATOR | Divya Bali, Shorena Janelidze, Gemma Salvadó, Geidy E Serrano, Thomas G Beach, Andreas Jeromin, Oskar Hansson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |