Brain age correlates with plasma NfL in amyloid positive individuals
Saurabh Sihag, Alejandro Ribeiro · 2025
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Description
Saurabh Sihag and Alejandro Ribeiro studied brain age and a blood marker in 2025. Brain age is a guess of how old a brain looks, made by a learning model from brain scans. The gap between that guess and true age can signal fast aging. The blood marker, called NfL, rises when nerve fibers break down.
The team used data from a large study of older adults. Groups held healthy adults and people with mild memory loss or dementia. All had amyloid signs in the brain. They found that brain age tracked the blood marker in these groups. The link may help doctors spot decline risk with simpler tests.
Catalog record
| CREATOR | Saurabh Sihag, Alejandro Ribeiro |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |