Parental history of dementia does not confound the association between depression and decline in cognitive status
Chad Guilliams, Erin L. Abner · 2025
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Description
Chad Guilliams and Erin Abner test whether a parent's history of dementia skews the known link between low mood and thinking loss, in a 2025 conference paper. Family history can pull certain people into studies, which may bend results. Many teams now swap it for gene marks instead.
The team sorted nearly twenty-one thousand adults without dementia by mood and thinking state at their first visit. People with low mood had more than twice the odds of mild thinking loss. Adding a parent's history to the model barely moved that link, though it did shift it a touch upward. The authors also tracked who slid to worse states over time, using death as a rival outcome in the models.
Catalog record
| CREATOR | Chad Guilliams, Erin L. Abner |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |