Bone morphogenetic protein levels relate to osteoarthritis and neurobehavioral outcomes in cognitively unimpaired older adults

Valentina E. Diaz, Emily W. Paolillo, Coty Chen, Anna M. VandeBunte, Claire J. Cadwallader, Charles A. Schurman, Birgit Schiling, Bruce L. Miller, Joel H. Kramer, Kaitlin B. Casaletto, Rowan Saloner · 2025

Read Bone morphogenetic protein levels relate to osteoarthritis and neurobehavioral outcomes in cognitively unimpaired older adults by Valentina E. Diaz, Emily W. Paolillo, Coty Chen, Anna M. VandeBunte, Claire J. Cadwallader, Charles A. Schurman, Birgit Schiling, Bruce L. Miller, Joel H. Kramer, Kaitlin B. Casaletto, Rowan Saloner (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714291.txt.

Description

Valentina Diaz and ten co-workers wrote a 2025 study on bone growth proteins in blood and their links to arthritis and brain measures in older adults. Bone and brain may talk through such circulating proteins. Participants were sixty-five cognitively healthy older adults in a brain aging study. About half had osteoarthritis on clinician exam.

Blood was assayed for eleven of these growth proteins. Memory and thinking scores were built from standard tests. Mood was scored with a geriatric depression scale. The team compared protein levels between arthritis and control groups, adjusting for age and sex. They then tested how arthritis-linked proteins tracked thinking and mood across all.

Catalog record

CREATORValentina E. Diaz, Emily W. Paolillo, Coty Chen, Anna M. VandeBunte, Claire J. Cadwallader, Charles A. Schurman, Birgit Schiling, Bruce L. Miller, Joel H. Kramer, Kaitlin B. Casaletto, Rowan Saloner
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714291

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