Predicting Cognitive Decline: A Comprehensive Study On relative Brain Age, Cognitive Reserve, And Longitudinal Changes
Mahboubeh Motaghi, Olivier Potvin, Valérie Turcotte, Iman Beheshti, Simon Duchesne · 2025
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Description
Mahboubeh Motaghi, Olivier Potvin, Valérie Turcotte, Iman Beheshti, and Simon Duchesne test whether a scan-based measure of brain aging can foresee fading memory and thinking. The measure compares a person's brain shape with peers of the same age: a brain that looks older than expected signals risk.
Following healthy adults and people with mild cognitive impairment for up to five years, the team linked the measure to change across four kinds of thinking skill. In the impairment group it helped explain who lost ground in word memory, and a learning model built on it predicted later scores with small errors. A reserve measure, built from schooling, job complexity, and verbal skill, also shaped the paths. The authors see promise for early warning.
Catalog record
| CREATOR | Mahboubeh Motaghi, Olivier Potvin, Valérie Turcotte, Iman Beheshti, Simon Duchesne |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |