Association of Plasma Alzheimer’s Disease Biomarkers with White Matter Hyperintensity Volume in Diverse Populations: A HABS‐HD Study
Antoine R Trammell, James J. Lah, Felicia Goldstein, Monica W Parker, Chadwick M Hales, Crystal P Davis, Cornelya D Dorbin, Sabria Saleh, Elizabeth Murphy‐Tchivzhel, Alecia Michella Rose, Sid E. O'Bryant · 2025
Read Association of Plasma Alzheimer’s Disease Biomarkers with White Matter Hyperintensity Volume in Diverse Populations: A HABS‐HD Study by Antoine R Trammell, James J. Lah, Felicia Goldstein, Monica W Parker, Chadwick M Hales, Crystal P Davis, Cornelya D Dorbin, Sabria Saleh, Elizabeth Murphy‐Tchivzhel, Alecia Michella Rose, Sid E. O'Bryant (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714276.txt.
Description
Blood tests for Alzheimer's markers are easier than brain scans, but their meaning may differ across racial groups. Antoine Trammell and ten co-authors studied 3,035 adults in 2025 from a health disparities cohort, comparing blood marker levels with the volume of white matter damage seen on MRI. The group spanned white, Black, and Hispanic participants, with and without thinking problems.
Black participants carried the most white matter damage, while white participants showed the highest levels of two blood markers. Links between the markers and damage volume appeared mainly in impaired Hispanic participants. The authors say blood markers cannot be read the same way in every group. They call for more work on what drives these gaps.
Catalog record
| CREATOR | Antoine R Trammell, James J. Lah, Felicia Goldstein, Monica W Parker, Chadwick M Hales, Crystal P Davis, Cornelya D Dorbin, Sabria Saleh, Elizabeth Murphy‐Tchivzhel, Alecia Michella Rose, Sid E. O'Bryant |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |