Sex‐specific differences in the association between regional adiposity, cognition, and brain pathology in older adults with Type II Diabetes

Ethel Boccara, Sapir Golan, Ithamar Ganmore, Ramit Ravona‐Springer, Abigail Livny, Mery Ben‐Meir, Yossi Azuri, Aron Weller, Michal S Beeri · 2025

Read Sex‐specific differences in the association between regional adiposity, cognition, and brain pathology in older adults with Type II Diabetes by Ethel Boccara, Sapir Golan, Ithamar Ganmore, Ramit Ravona‐Springer, Abigail Livny, Mery Ben‐Meir, Yossi Azuri, Aron Weller, Michal S Beeri (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714246.txt.

Description

Where fat sits in the body may matter for the brain in older adults with type 2 diabetes, and Ethel Boccara and co-authors test that idea by sex in this 2025 study. Body mass index says nothing about fat around organs, which differs between men and women. The study used belly scans to measure liver, pancreas, and deep belly fat.

Just over one hundred participants took thinking tests, and about half also had brain scans. Across the whole group, more pancreas fat came close to tracking with weaker overall thinking. In men, but not in women, high pancreas fat linked clearly to lower scores. The authors frame fat distribution as a sex-specific piece of the diabetes-brain puzzle.

Catalog record

CREATOREthel Boccara, Sapir Golan, Ithamar Ganmore, Ramit Ravona‐Springer, Abigail Livny, Mery Ben‐Meir, Yossi Azuri, Aron Weller, Michal S Beeri
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714246

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