Differential network‐based propagation of cortical thinning in atrophy subtypes in non‐demented individuals
Luigi Lorenzini, Mario Tranfa, Leonard Pieperhoff, Mara ten Kate, Giuseppe Pontillo, Isadora Lopes Alves, Mahnaz Shekari, Daniele Altomare, Anouk den Braber, Craig W Ritchie, Mercè Boada, Marta Marquié, Rik Vandenberghe, Emma S Luckett, Bernard J Hanseeuw, Pieter Jelle Visser, Michael Schöll, Giovan · 2025
Read Differential network‐based propagation of cortical thinning in atrophy subtypes in non‐demented individuals by Luigi Lorenzini, Mario Tranfa, Leonard Pieperhoff, Mara ten Kate, Giuseppe Pontillo, Isadora Lopes Alves, Mahnaz Shekari, Daniele Altomare, Anouk den Braber, Craig W Ritchie, Mercè Boada, Marta Marquié, Rik Vandenberghe, Emma S Luckett, Bernard J Hanseeuw, Pieter Jelle Visser, Michael Schöll, Giovan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714058.txt.
Description
Luigi Lorenzini and co-authors study patterns of brain thinning in people without dementia in a 2025 paper. Different thinning patterns are known in the dementia stage of Alzheimer's disease, but less is known early on. The team used brain scans from more than thirteen hundred people in a European cohort. Most had no protein buildup in the brain, and some did. They grouped people by their pattern of thinning across brain areas.
Three patterns stood out, described as limbic led, typical Alzheimer's type, and spread across the outer brain. The team then modeled how thinning in one area may spread along brain links over time. Each pattern spread in its own way. Readers learn why early Alzheimer's may follow more than one path through the brain.
Catalog record
| CREATOR | Luigi Lorenzini, Mario Tranfa, Leonard Pieperhoff, Mara ten Kate, Giuseppe Pontillo, Isadora Lopes Alves, Mahnaz Shekari, Daniele Altomare, Anouk den Braber, Craig W Ritchie, Mercè Boada, Marta Marquié, Rik Vandenberghe, Emma S Luckett, Bernard J Hanseeuw, Pieter Jelle Visser, Michael Schöll, Giovan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |