Influence of tau on non‐traditional memory scores in early‐onset Alzheimer’s disease
Ralitsa V Kostadinova, Justin Bushnell, Dustin B Hammers, Liana G Apostolova, David G Clark · 2025
Read Influence of tau on non‐traditional memory scores in early‐onset Alzheimer’s disease by Ralitsa V Kostadinova, Justin Bushnell, Dustin B Hammers, Liana G Apostolova, David G Clark (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714020.txt.
Description
Ralitsa Kostadinova and co-authors present a conference report, published in 2025, linking brain tau deposits to memory test patterns in early onset Alzheimer's disease. The standard test asks people to learn and recall word lists over several rounds. The team transcribed recordings from about two hundred and fifty subjects in a national study of early onset disease and built three combined scores from the test.
Brain scans measured tau, a protein that tangles inside nerve cells, across more than one hundred regions. Patterns of tau spread were reduced to a few main components and tested against the memory scores. Early results show the strongest component loaded across nearly the whole brain. The work aims to tie simple test scores to the biology driving early memory loss.
Catalog record
| CREATOR | Ralitsa V Kostadinova, Justin Bushnell, Dustin B Hammers, Liana G Apostolova, David G Clark |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |