Potentially modifiable risk factors for dementia putting the evidence together: Total population attributable fraction

Gill Livingston, Jonathan D Huntley, Kathy Y Liu, Sergi Costafreda Gonzalez, Geir Selbaek, Suvarna Alladi, David Ames, Sube Banerjee, Alistair Burns, Carol Brayne, Nick C Fox, Cleusa P Ferri, Laura N Gitlin, Robert J Howard, Helen C Kales, Mika Kivimaki, Eric B Larson, Noeline Nakasujja, Kenneth Roc · 2025

Read Potentially modifiable risk factors for dementia putting the evidence together: Total population attributable fraction by Gill Livingston, Jonathan D Huntley, Kathy Y Liu, Sergi Costafreda Gonzalez, Geir Selbaek, Suvarna Alladi, David Ames, Sube Banerjee, Alistair Burns, Carol Brayne, Nick C Fox, Cleusa P Ferri, Laura N Gitlin, Robert J Howard, Helen C Kales, Mika Kivimaki, Eric B Larson, Noeline Nakasujja, Kenneth Roc (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11714002.txt.

Description

Gill Livingston and a large team of co-authors totaled the share of dementia that could in principle be prevented, in a 2025 paper. Many risk factors for dementia are changeable over a life: schooling, hearing, blood pressure, smoking, and more. Each factor's share has been estimated before, but adding them up fairly is tricky because they overlap in the same people.

The authors put the evidence together into one population attributable fraction, the share of cases tied to all the changeable factors combined. A single honest number helps governments weigh dementia prevention against other health spending. It also sets a ceiling: even perfect action on every factor cannot pass that share.

Catalog record

CREATORGill Livingston, Jonathan D Huntley, Kathy Y Liu, Sergi Costafreda Gonzalez, Geir Selbaek, Suvarna Alladi, David Ames, Sube Banerjee, Alistair Burns, Carol Brayne, Nick C Fox, Cleusa P Ferri, Laura N Gitlin, Robert J Howard, Helen C Kales, Mika Kivimaki, Eric B Larson, Noeline Nakasujja, Kenneth Roc
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11714002

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