Unleashing the power of a willow bark‐derived tannin to alleviate behavioral deficits in a preclinical model of Alzheimer’s disease
Ezaldean A Kahil, Anisha Jackson, Kruti Patel, Lori A Coward, Bernadette D'Souza, Gregory Gorman, Patricia Jumbo‐Lucioni · 2025
Read Unleashing the power of a willow bark‐derived tannin to alleviate behavioral deficits in a preclinical model of Alzheimer’s disease by Ezaldean A Kahil, Anisha Jackson, Kruti Patel, Lori A Coward, Bernadette D'Souza, Gregory Gorman, Patricia Jumbo‐Lucioni (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713971.txt.
Description
Ezaldean Kahil and co-authors test a willow bark compound in a fruit fly model of Alzheimer's disease in a 2025 study. No cure exists for the disease, whose marks include brain swelling and cell stress plus steady loss of movement and thinking. The compound has shown strong protective effects in lab dishes, but live animal proof was thin. Flies were bred to make human proteins linked to the disease in nerve cells.
Young sick flies moved more slowly than controls in a climbing test. Adding the compound to food eased those movement flaws in young flies of both sexes. The team also checked how flies coped with a stress chemical and measured compound breakdown products. Readers see early live evidence for a cheap plant based lead.
Catalog record
| CREATOR | Ezaldean A Kahil, Anisha Jackson, Kruti Patel, Lori A Coward, Bernadette D'Souza, Gregory Gorman, Patricia Jumbo‐Lucioni |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |