MRI Correlates of Executive Function in Cognitively Normal Older Subjects

Banafsheh Shakibajahromi, Sudipto Dolui, Christopher Brown, Mohammad Taghvaei, Pulkit Khandelwal, Qichao Wu, Shokufeh Sadaghiani, Paul A Yushkevich, David A Wolk, John A Detre · 2025

Read MRI Correlates of Executive Function in Cognitively Normal Older Subjects by Banafsheh Shakibajahromi, Sudipto Dolui, Christopher Brown, Mohammad Taghvaei, Pulkit Khandelwal, Qichao Wu, Shokufeh Sadaghiani, Paul A Yushkevich, David A Wolk, John A Detre (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713890.txt.

Description

Banafsheh Shakibajahromi and co-authors link brain scans to thinking skills in a 2025 study of older adults. The group held 133 adults over age 50 whose thinking was still normal. Small vessel disease in the brain is a top cause of thinking loss tied to blood flow. Its early signs include weak planning skills and spots in white matter, the brain's wiring.

The team used a trail-making test to score planning skill. Scans measured blood flow and wiring health in white matter that still looked normal. They split the group by amyloid state, a protein sign tied to Alzheimer's disease. Risk factors such as high blood pressure and diabetes were counted in the math as well.

Catalog record

CREATORBanafsheh Shakibajahromi, Sudipto Dolui, Christopher Brown, Mohammad Taghvaei, Pulkit Khandelwal, Qichao Wu, Shokufeh Sadaghiani, Paul A Yushkevich, David A Wolk, John A Detre
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11713890

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