Unveiling the Multifaceted Neuroprotection of Dihydroxytrimethoxyflavone: Memory Enhancement Beyond Cholinergic Boost
Varinder Singh, Manjinder Singh, Richa Shri · 2025
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Description
Varinder Singh, Manjinder Singh, and Richa Shri test a plant compound in mice in a 2025 study. The compound is a flavone, a natural substance found in herbal drugs. Lead exposure harms memory, so the team used lead to model memory loss. They ask whether the compound protects the brain through more than one path, not just the usual signal-based route.
Mice got lead each day for twenty-eight days, and some also got the compound an hour before. The treated mice did better in a water maze test of memory. Their brains showed less of a memory-blocking enzyme and less amyloid buildup. Levels of a protective protein and its helper proteins also rose, which points to a defense switch being turned on.
Catalog record
| CREATOR | Varinder Singh, Manjinder Singh, Richa Shri |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |