The Relationship of Neuropsychiatric Symptoms and ADRD Pathologies

Julia R Bacci, Marc D Rudolph, Michelle M Mielke, Suzanne Craft, James R Bateman, Samuel N Lockhart · 2025

Read The Relationship of Neuropsychiatric Symptoms and ADRD Pathologies by Julia R Bacci, Marc D Rudolph, Michelle M Mielke, Suzanne Craft, James R Bateman, Samuel N Lockhart (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713831.txt.

Description

Julia Bacci and co-authors ask how mood and behavior symptoms link to brain harm in older adults, in a study from 2025. Such symptoms are common as memory fades, but their roots are still unclear. The team studied close to six hundred adults, some with normal thought and some with mild loss, in a mixed race group from one research center.

The team linked symptom scores to white matter harm seen on scans and to a blood marker of nerve harm. White matter harm linked to worse symptoms in White adults but to milder symptoms in Black adults. The blood marker linked to worse symptoms only in those with mild loss of thought. The authors say more work with more markers is needed to sort out these mixed links.

Catalog record

CREATORJulia R Bacci, Marc D Rudolph, Michelle M Mielke, Suzanne Craft, James R Bateman, Samuel N Lockhart
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11713831

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