Creating Universal Tau PET Scale (Uniτ) Parametric Images – The HEAD Study
Guilherme Povala, Guilherme Bauer‐Negrini, Bruna Bellaver, Firoza Z Lussier, Livia Amaral, Pamela C.L. Ferreira, Quentin Finn, Bruno Zatt, Dana Tudorascu, William J. Jagust, William E Klunk, Val J. Lowe, David N. Soleimani‐Meigooni, Hwamee Oh, Belen Pascual, Brian A. Gordon, Pedro Rosa‐Neto, Suzanne · 2025
Read Creating Universal Tau PET Scale (Uniτ) Parametric Images – The HEAD Study by Guilherme Povala, Guilherme Bauer‐Negrini, Bruna Bellaver, Firoza Z Lussier, Livia Amaral, Pamela C.L. Ferreira, Quentin Finn, Bruno Zatt, Dana Tudorascu, William J. Jagust, William E Klunk, Val J. Lowe, David N. Soleimani‐Meigooni, Hwamee Oh, Belen Pascual, Brian A. Gordon, Pedro Rosa‐Neto, Suzanne (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713824.txt.
Description
Guilherme Povala and co-authors present a shared scale for tau brain scans in a 2025 paper. Different scan tracers measure tau, the second hallmark protein of Alzheimer's, on different scales. Results from one tracer cannot be compared directly with another. The team builds a universal scale that converts each scan type into common units.
The study covers 185 people across the aging and Alzheimer's range. Each person was scanned with one of two common tau tracers. A set formula, anchored on young adults and on patients, converts the images to the shared scale. Common units would let hospitals and trials pool scan data. That pooling speeds research on how tau spreads and how drugs slow it.
Catalog record
| CREATOR | Guilherme Povala, Guilherme Bauer‐Negrini, Bruna Bellaver, Firoza Z Lussier, Livia Amaral, Pamela C.L. Ferreira, Quentin Finn, Bruno Zatt, Dana Tudorascu, William J. Jagust, William E Klunk, Val J. Lowe, David N. Soleimani‐Meigooni, Hwamee Oh, Belen Pascual, Brian A. Gordon, Pedro Rosa‐Neto, Suzanne |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |