Imaging biomarker of beta‐amyloid pathology limits cognitive plasticity in healthy aging: A multi‐center intervention study
Gérard N Bischof, Tim Fellerhoff, Kathrin Giehl, Alexander Drzezga · 2025
Read Imaging biomarker of beta‐amyloid pathology limits cognitive plasticity in healthy aging: A multi‐center intervention study by Gérard N Bischof, Tim Fellerhoff, Kathrin Giehl, Alexander Drzezga (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713816.txt.
Description
Gérard Bischof and co-authors ask whether amyloid in the brain limits gains from memory training in a 2025 study. Older adults can still improve thinking skills with practice, even late in life. People vary a lot in how much they gain, though. The team tests whether silent amyloid buildup, seen on brain scans, explains part of that gap.
Seventy-six healthy older adults took twelve hour-long training sessions. The tasks covered attention, memory, speed, and planning. Brain scans measured amyloid before the training began. Tests ran before training, right after, and again three months later. People with more amyloid gained less from the same practice. The finding may help clinics set fair hopes for brain training programs.
Catalog record
| CREATOR | Gérard N Bischof, Tim Fellerhoff, Kathrin Giehl, Alexander Drzezga |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |