Contrast of Early Phase Amyloid PET
Masashi Kameyama, Muneyuki Sakata, Kenji Ishibashi, Tetsuro Tago, Yuto Kamitaka, Jun Toyohara, Kenji Ishii · 2025
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Description
Masashi Kameyama and co-authors work on the contrast of early phase images from amyloid PET scans of the brain. Published in 2025, the paper explains that the first minutes of such a scan can give a stand-in image of blood flow. That image flags both amyloid buildup and sites of nerve cell loss. The catch is that the early image is not a true blood flow image, so its contrast suffers.
The team built a method to recover that contrast. They also built a way to set its key parameter, grounded in a literature review. Early images from one tracer tracked a standard glucose scan closely. Mild underestimates appeared where blood flow was high. The authors set out the theory for wider use.
Catalog record
| CREATOR | Masashi Kameyama, Muneyuki Sakata, Kenji Ishibashi, Tetsuro Tago, Yuto Kamitaka, Jun Toyohara, Kenji Ishii |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |