Body mass index moderates the relationship between the apnea‐hypopnea index and CSF biomarker of activated microglia
Julia Bink, Yue Ma, Bryce A Mander, David T Plante, Margherita Carboni, Norbert Wild, Nathaniel A Chin, Ozioma C Okonkwo, Cynthia M Carlsson, Carey E Gleason, Sanjay Asthana, Sterling C Johnson, Kaj Blennow, Henrik Zetterberg, Ruth M Benca, Barbara B Bendlin · 2025
Read Body mass index moderates the relationship between the apnea‐hypopnea index and CSF biomarker of activated microglia by Julia Bink, Yue Ma, Bryce A Mander, David T Plante, Margherita Carboni, Norbert Wild, Nathaniel A Chin, Ozioma C Okonkwo, Cynthia M Carlsson, Carey E Gleason, Sanjay Asthana, Sterling C Johnson, Kaj Blennow, Henrik Zetterberg, Ruth M Benca, Barbara B Bendlin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713598.txt.
Description
Julia Bink and co-authors published a study in 2025 on sleep apnea, body weight, and brain fluid markers of immune activity. Past work links apnea to Alzheimer disease markers, but links to other brain harm markers are less known. The team asked whether body mass index changes the link between apnea severity and one marker of active microglia, the brain's immune cells. The study was cross-sectional.
Seventy-three adults with sound thinking and no prior apnea diagnosis had sleep tests and a spinal fluid draw. Apnea severity alone showed no link to any fluid marker. But body mass shaped one link: at lower body mass, worse apnea tied to higher levels of the microglia marker. That tie faded as body mass rose.
Catalog record
| CREATOR | Julia Bink, Yue Ma, Bryce A Mander, David T Plante, Margherita Carboni, Norbert Wild, Nathaniel A Chin, Ozioma C Okonkwo, Cynthia M Carlsson, Carey E Gleason, Sanjay Asthana, Sterling C Johnson, Kaj Blennow, Henrik Zetterberg, Ruth M Benca, Barbara B Bendlin |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |