Study entry, change, and death: learning from decades of follow‐up in clinical‐pathologic studie
Ana W Capuano, Lisa L Barnes, Julie A Schneider, David A Bennett · 2025
Read Study entry, change, and death: learning from decades of follow‐up in clinical‐pathologic studie by Ana W Capuano, Lisa L Barnes, Julie A Schneider, David A Bennett (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713575.txt.
Description
Ana Capuano, Lisa Barnes, Julie Schneider, and David Bennett draw lessons from decades of brain aging follow-up, in this 2025 paper. Dementia hits some groups harder, yet those groups are scarce in trials. The team works with four long studies that pair yearly thinking tests with brain study after death, the oldest running since 1994.
Curves of thinking over age bend in complex ways: a small practice lift at the start, then a long nonlinear slide. The team compares paths by race, ethnicity, brain findings, and insulin resistance. They also test how much of each path a short trial could see with standard score blends. The authors aim the lessons at fairer, smarter trial design.
Catalog record
| CREATOR | Ana W Capuano, Lisa L Barnes, Julie A Schneider, David A Bennett |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |