Effort‐based decision making and white matter tracts associated with dimensions of apathy in Alzheimer’s and Parkinson’s disease
Yunglin Gazes, Seonjoo Lee, Zekai Jin, Bryan Chen, Edward D Huey, Sarah Heibronner, Campbell Le Heron, Nora Vanegas · 2025
Read Effort‐based decision making and white matter tracts associated with dimensions of apathy in Alzheimer’s and Parkinson’s disease by Yunglin Gazes, Seonjoo Lee, Zekai Jin, Bryan Chen, Edward D Huey, Sarah Heibronner, Campbell Le Heron, Nora Vanegas (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713492.txt.
Description
Gazes and co-authors study apathy and effort-based choices in Alzheimer's and Parkinson's disease, in this 2025 paper. Apathy means low drive and less goal-seeking, and it is common in both diseases. The team uses a game-like task where players weigh effort against reward.
Patients took an apathy scale and played an apple-gathering task that gauges how effort and reward sway choices. Brain scans measured the health of white matter paths that link front brain areas to deeper ones. Math models join the three kinds of data. Early results aim to show which brain paths underlie each side of apathy.
Catalog record
| CREATOR | Yunglin Gazes, Seonjoo Lee, Zekai Jin, Bryan Chen, Edward D Huey, Sarah Heibronner, Campbell Le Heron, Nora Vanegas |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |