The importance of AT(N)‐V imaging biomarkers differs in diverse populations
Karin L Meeker · 2025
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Description
Karin Meeker wrote this study, published in two thousand twenty-five, on how Alzheimer's staging markers work across racial and ethnic groups. The staging frame sorts people by amyloid, tau, brain shrinkage, and vessel damage, but most past work used white clinic samples.
Meeker used a large community study with Mexican American, African American, and non-Hispanic white adults. Marker levels differed by group in the full sample, though not among those already amyloid positive. Amyloid was the top predictor of thinking status overall and in the two minority groups. Tau mattered most in the white group. Among amyloid-positive people, shrinkage led in the minority groups. The author warns that one staging recipe may not fit all groups. Trials and clinics should weigh group differences when they read these scans.
Catalog record
| CREATOR | Karin L Meeker |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |