The association between the age and the rate of tau accumulation and spreading in different sexes
Zeyu Zhu, Amir Dehsarvi, Sebastian Niclas Roemer, Anna Steward, Anna Dewenter, Mattes Gross, Fabian Wagner, Michael Ewers, Matthias Brendel, Nicolai Franzmeier · 2025
Read The association between the age and the rate of tau accumulation and spreading in different sexes by Zeyu Zhu, Amir Dehsarvi, Sebastian Niclas Roemer, Anna Steward, Anna Dewenter, Mattes Gross, Fabian Wagner, Michael Ewers, Matthias Brendel, Nicolai Franzmeier (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713479.txt.
Description
Zeyu Zhu and co-authors ask how age and sex shape the spread of tau in the brain, in this 2025 paper. Tau build-up drives much of the harm in Alzheimer's disease. Scans show that its path differs by age and sex, but the reasons are unclear.
The study covered three hundred thirteen people from a national data set, some healthy and some across the disease range. Each had amyloid scans and repeat tau scans over time. The team mapped yearly tau change in two hundred brain areas and used brain wiring maps from other adults. They test how age, sex, and amyloid jointly steer where tau grows and spreads.
Catalog record
| CREATOR | Zeyu Zhu, Amir Dehsarvi, Sebastian Niclas Roemer, Anna Steward, Anna Dewenter, Mattes Gross, Fabian Wagner, Michael Ewers, Matthias Brendel, Nicolai Franzmeier |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |