Derivation and Validation of the Cognitive Impairment Prediction Model in Older Adults: A National Cohort Study

Mingyue Hu · 2025

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Description

Mingyue Hu builds a tool that estimates an older person's chance of developing cognitive impairment over six years. The model comes from a national Chinese longevity survey, using 10,053 participants followed for a median of about five and a half years. In that time, 1,750 people, about seventeen percent, developed impairment, and many others died, which the analysis treats as a competing risk.

Eight easy-to-collect factors drive the predictions, chosen with a mix of statistics and clinical judgment. The model separates future cases from non-cases fairly well and held up when tested on an earlier survey wave. It works best in the younger old, ages sixty-five to seventy-four. Nearly half the impairment risk traces to factors people can change.

Catalog record

CREATORMingyue Hu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11713466

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